Download E-books Force Microscopy: Applications in Biology and Medicine PDF

An entire exam of the makes use of of the atomic strength microscope in biology and medicine

This state-of-the-art textual content, written through a workforce of prime specialists, is the 1st specified exam of the newest, strongest scanning probe microscope, the atomic strength microscope (AFM). utilizing the AFM, together with traditional instruments and methods, readers achieve a profound knowing of the mobile, subcellular organelles, and biomolecular constitution and function.

The textual content starts off with 3 chapters describing the molecular equipment and mechanism of cellphone secretion and membrane fusion in cells, utilizing ways that mix AFM, electron microscopy, X-ray diffraction, photon correlation spectroscopy, molecular biology, biochemistry, and electrophysiology. the invention of a brand new mobile constitution the "porosome" or fusion pore--the cells secretory equipment, the molecular mechanism of membrane fusion in cells, and the expulsion of intravesicular contents in the course of telephone secretion are defined within the first 3 chapters. The publication additionally covers:
* id of the "porosome" within the development hormone secreting mobile of the pituitary gland
* Probing the structural and actual homes of microbial cellphone surfaces
* Scanning probe microscopic characterization of the better plant telephone wall and its components
* Case reviews of nano drug supply structures utilizing engineered dendrimers
* AFM strategies for learning residing cells
* Investigating the intermolecular forces of leukocyte adhesion molecules
* Protein-protein interactions
* Micromechanical homes of lipid bilayers and vesicles

The textual content concludes with 4 chapters that study new and rising methods within the use of strength microscopy in biology and medicine.

this article is perfect for complicated undergraduate and graduate scholars and researchers in mobilephone and molecular biology, genetics, genomics, body structure, neuroscience, biophysics, and biochemistry. not just does it give you the conception, but in addition sensible concerns akin to the choice of the suitable instruments and method.

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